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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 22.42
Human Site: T941 Identified Species: 30.83
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T941 Y P S T L V R T E P R E H L L
Chimpanzee Pan troglodytes XP_507923 1056 119132 T941 Y P S T L V R T E P R E H L L
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 V750 I Q K P L S S V Q E D I Q Q K
Dog Lupus familis XP_534964 1334 149091 T1223 Y P S T L V R T E P R E Q L L
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T940 Y P T T L V R T E P R E Q L L
Rat Rattus norvegicus O55165 796 89797 Y693 Y K R P I S Q Y A R V A M A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Q996 Q E N D V L K Q K M L L V Q V
Frog Xenopus laevis P28025 1060 119314 T945 Y P S L L V K T K P R D V L L
Zebra Danio Brachydanio rerio NP_775368 955 106984 T852 K L I R Q T D T A V Q D L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 T948 Y P R T L V A T S P H Q E I V
Honey Bee Apis mellifera XP_623508 706 80766 V603 C K I A F M N V S I E M S Q K
Nematode Worm Caenorhab. elegans P46873 699 78760 N596 T I L P L A N N G Y M Q E P A
Sea Urchin Strong. purpuratus P46872 699 78679 Q596 I I D S F I P Q E F Q E M I E
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 H951 Q L K G S H Y H K I V E I T E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 E937 C I E D K A Q E T F Q Q Q Y M
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 D996 I K A L P L L D Y P K Q F Q I
Red Bread Mold Neurospora crassa P48467 928 102392 R825 A E R K L M A R N E R I Q S L
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 93.3 N.A. 86.6 6.6 N.A. N.A. 0 66.6 13.3 N.A. 46.6 0 6.6 13.3
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 26.6 N.A. N.A. 40 86.6 26.6 N.A. 66.6 6.6 13.3 40
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 0 6.6 20
P-Site Similarity: 13.3 N.A. N.A. 26.6 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 6 0 12 12 0 12 0 0 6 0 6 6 % A
% Cys: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 12 0 0 6 6 0 0 6 12 0 0 0 % D
% Glu: 0 12 6 0 0 0 0 6 30 12 6 36 12 0 12 % E
% Phe: 0 0 0 0 12 0 0 0 0 12 0 0 6 0 0 % F
% Gly: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 6 0 6 0 0 6 0 12 0 0 % H
% Ile: 18 18 12 0 6 6 0 0 0 12 0 12 6 12 6 % I
% Lys: 6 18 12 6 6 0 12 0 18 0 6 0 0 0 18 % K
% Leu: 0 12 6 12 53 12 6 0 0 0 6 6 6 36 36 % L
% Met: 0 0 0 0 0 12 0 0 0 6 6 6 12 0 12 % M
% Asn: 0 0 6 0 0 0 12 6 6 0 0 0 0 0 0 % N
% Pro: 0 36 0 18 6 0 6 0 0 42 0 0 0 6 0 % P
% Gln: 12 6 0 0 6 0 12 12 6 0 18 24 30 24 0 % Q
% Arg: 0 0 18 6 0 0 24 6 0 6 36 0 0 0 0 % R
% Ser: 0 0 24 6 6 12 6 0 12 0 0 0 6 6 0 % S
% Thr: 6 0 6 30 0 6 0 42 6 0 0 0 0 6 0 % T
% Val: 0 0 0 0 6 36 0 12 0 6 12 0 12 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 42 0 0 0 0 0 6 6 6 6 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _